Everyday soundscapes dynamically engage attention towards target sounds or salient ambient events, with both attentional forms engaging the same fronto-parietal network but in a push-pull competition for limited neural resources.
Embryonic lethality associated with deficiency of UBIAD1, which synthesizes a vitamin K2 subtype, results from aberrant ER-associated degradation of the cholesterol biosynthetic enzyme HMG CoA reductase.
Multiplexing and digital analysis of melanoma tissue describe functionally the microenvironment associated with brisk/non-brisk infiltrates and expose the functional incongruences of this morphological classification currently in use for tumor-infiltrating lymphocytes.
APP mutations that either cause or prevent dementia alter APP metabolism in a complex and opposite fashion, suggesting a link between multiple APP processing events, dementia and ageing-dependent cognitive decline.
CNApp is a novel and unique web-based software that enables the performance of comprehensive and integrative analysis of genomic copy number alterations to uncover new associations with patient-oriented relevance.