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    1. Ecology
    2. Physics of Living Systems

    Extreme suction attachment performance from specialised insects living in mountain streams (Diptera: Blephariceridae)

    Victor Kang, Robin T White ... Walter Federle
    Net-winged midge larvae use suction organs covered in spine-like cuticular protrusions to generate powerful attachment on wet and rough surfaces.
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

    David R Shook, Eric M Kasprowicz ... Raymond Keller
    Blastopore closure in Xenopus is driven by two morphogenic mechanisms that have strongly context dependent effects on tissue movement and that generate tensile force across tissues: convergent extension, as expected, and, unexpectedly, convergent thickening.
    1. Computational and Systems Biology
    2. Neuroscience

    Phase response analyses support a relaxation oscillator model of locomotor rhythm generation in Caenorhabditis elegans

    Hongfei Ji, Anthony D Fouad ... Christopher Fang-Yen
    Behavioral, optogenetic, and computational modeling analyses show that the roundworm Caenorhabditis elegans uses a relaxation oscillation mechanism to generate rhythmic locomotor patterns.
    1. Neuroscience

    Drosophila uses a tripod gait across all walking speeds, and the geometry of the tripod is important for speed control

    Chanwoo Chun, Tirthabir Biswas, Vikas Bhandawat
    Drosophila uses a gait close to the tripod throughout its speed range, and changes in speed are accompanied by changes in the geometry of the tripod.
    1. Cell Biology

    Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

    Mark G Jones, Orestis G Andriotis ... Donna E Davies
    Nanoscale changes to individual collagen fibrils drive lung fibrosis.
    1. Evolutionary Biology

    New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins

    Natalia Jagielska, Thomas G Kaye ... Michael Pittman
    Laser-stimulated fluorescence (LSF) imaging of early pterosaurs uncovers new soft tissue data of tail vane that reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins.
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    1. Cancer Biology

    Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

    Mee Rie Sheen, Jennifer L Fields ... Reproducibility Project: Cancer Biology
    Editors' Summary: This Replication Study has reproduced some parts of the original paper but other parts could not be interpreted.
    1. Computational and Systems Biology
    2. Neuroscience

    Contrasting action and posture coding with hierarchical deep neural network models of proprioception

    Kai J Sandbrink, Pranav Mamidanna ... Alexander Mathis
    To isolate and study proprioception, hierarchical deep neural networks paired with biomechanical models provide a normative approach to test the role of task effects on neural representations, such as the emergence of kinematic tuning and higher-level abstractions of actions.
    1. Neuroscience

    Cortex-dependent recovery of unassisted hindlimb locomotion after complete spinal cord injury in adult rats

    Anitha Manohar, Guglielmo Foffani ... Karen A Moxon
    After complete spinal transection in adult rats, careful combinations of pharmacological and physical therapies create a novel cortical sensorimotor circuit that may bypass the lesion through biomechanical coupling, allowing animals to recover unassisted hindlimb locomotion.