334 results found
  1. Cutting Edge: Towards PubMed 2.0

    Nicolas Fiorini et al.
    Staff from the National Center for Biotechnology Information in the US describe recent improvements to the PubMed search engine and outline plans for the future, including a new experimental site called PubMed Labs.
  2. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
  3. Point of View: Overflow in science and its implications for trust

    Sabina Siebert et al.
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons et al.
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
  4. Point of View: The future of graduate and postdoctoral training in the biosciences

    Peter Hitchcock et al.
    What can institutions and funding agencies do to address an array of issues facing the biomedical research community in the United States?
  5. Plain-language Summaries of Research: Something for everyone

    Sarah Shailes
    Journals and other scientific organizations produce a diverse variety of plain-language summaries.
  6. Research: Financial costs and personal consequences of research misconduct resulting in retracted publications

    Andrew M Stern et al.
    In the first study attempting to formally quantify the deleterious impact of research misconduct on funding sources and publication output, we found that misconduct accounts for a small but substantial portion of American biomedical science funding dollars and damages the productivity and rate of funding acquisition of those who commit misconduct.
  7. Point of View: The writing on the wall

    Henry R Bourne
    The biomedical research enterprise in the US has become unsustainable and urgent action is needed to address a variety of problems.
    1. Cancer Biology

    Science Forum: Challenges in validating candidate therapeutic targets in cancer

    Jeffrey Settleman et al.
    More than 30 published articles have suggested that a protein kinase called MELK is an attractive therapeutic target in human cancer, but three recent reports describe compelling evidence that it is not.
  8. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.

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