Browse the search results

Page 3 of 21
    1. Neuroscience

    Node of Ranvier length as a potential regulator of myelinated axon conduction speed

    I Lorena Arancibia-Cárcamo et al.
    Node of Ranvier length is similar at successive nodes along single myelinated CNS axons, but differs between axons, and could potentially be tuned to adjust the conduction velocity of each axon.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Symmetry breaking in reconstituted actin cortices

    Enas Abu Shah, Kinneret Keren
    A reconstituted system has been developed that self-organizes into dynamic actin cortices capable of spontaneous polarization, similar to the initial cortical polarization observed in cells during embryogenesis and development.
    1. Biochemistry and Chemical Biology

    Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions

    Xi Peng et al.
    Affinity capture of polyribosomes followed by RNAseq(ACAPSeq) is a technique that harnesses massively parallel sequencing to identify protein-protein interactions from any source from which polyribosomes can be purified.
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38

    Christopher P Arnold et al.
    An innate immune system signaling pathway in planarians has a dual role: it enhances apoptosis during bacterial infection, but represses apoptosis during tissue regeneration in the absence of infection.
    1. Developmental Biology

    Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering

    Daniel Šmít et al.
    Competition between adhesive and tensile forces regulates axon fasciculation, thus introducing a new role of mechanical tension in the development of neural networks.
    1. Genetics and Genomics
    2. Medicine

    EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence

    Jeremie Gautheron et al.
    Disruption of epoxide hydrolysis inducing oxidative stress and cellular senescence is a novel mechanism responsible for lipoatrophic monogenic diabetes.
    1. Evolutionary Biology

    Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species

    Thomas Sakoparnig et al.
    For many bacterial species, recombination dominates genome evolution and phylogenetic patterns that have so far been assumed to reflect clonal relationships, in fact reflect variation in recombination rates across lineages.
    1. Microbiology and Infectious Disease

    BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

    Teresa del Peso Santos et al.
    Vibrio cholerae uses a conserved ribosome assembly factor to repress biofilm formation at low temperatures.
    1. Neuroscience

    Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

    Opeyemi O Alabi et al.
    Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.
    1. Neuroscience

    Massive cortical reorganization in sighted Braille readers

    Katarzyna Siuda-Krzywicka et al.
    Teaching a tactile alphabet to sighted adults reveals the brain’s unexpected potential for change.