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    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Puromycin reactivity does not accurately localize translation at the subcellular level

    Syed Usman Enam et al.
    Methods that use puromycin to localize active translation do not actually detect the site of translation.
    1. Developmental Biology
    2. Neuroscience

    Shifts in myeloarchitecture characterise adolescent development of cortical gradients

    Casey Paquola et al.
    Layer-specific microstructural changes contribute to the maturation of cortical organisation during adolescence.
    1. Ecology
    2. Evolutionary Biology

    Seminal fluid compromises visual perception in honeybee queens reducing their survival during additional mating flights

    Joanito Liberti et al.
    After insemination, honeybee queens experience a rapid reduction in vision and flight performance, consistent with an ongoing sexual conflict over the number of mating flights that queens embark on.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling

    Adam Graham Grieve et al.
    The iRhom2 protein, a catalytically inactive relative of rhomboid proteases, controls inflammation and growth factor signalling by acting as an essential multifunctional regulatory subunit of the cell surface shedding protease TACE (ADAM17).
    1. Neuroscience

    Cerebellar re-encoding of self-generated head movements

    Guillaume P Dugué et al.
    The cerebellum encodes self-generated head rotations in a head posture-dependent manner, providing in particular a representation of how the head rotates about axes referenced relative to gravity.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage

    Shun-Hsiao Lee et al.
    The crystal structure of human Holliday junction resolvase GEN1 in complex with DNA reveals a conserved chromodomain as an additional DNA-anchoring point that opens new perspectives for enzyme regulation.
    1. Computational and Systems Biology

    Neural oscillations as a signature of efficient coding in the presence of synaptic delays

    Matthew Chalk et al.
    Neural oscillations are a necessary consequence of efficient coding of sensory signals by a spiking neural network, limited by synaptic delays and noise.
    1. Cancer Biology
    2. Cell Biology

    TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration

    Amrutha Patkunarajah et al.
    A novel mechanoelectrical transduction pathway can regulate the interactions of melanoma cells and their surrounding microenvironment, impacting both migration and cell dissociation from organotypic spheroids.
    1. Computational and Systems Biology
    2. Neuroscience

    Speech encoding by coupled cortical theta and gamma oscillations

    Alexandre Hyafil et al.
    Computational modelling shows that coupled theta and gamma oscillations in the auditory cortex can decompose speech into its syllabic constituents, and organize the neural spiking at faster timescale into a decodable format.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Predicting evolution from the shape of genealogical trees

    Richard A Neher et al.
    A general method for inferring fitness from a sample of nucleotide sequences can predict the progenitor of next year's seasonal influenza.