A quantitative analysis of the connectivity between photoreceptors and bipolar cells in the mouse retina based on electron microscopy data yields exceptions from established rules of outer retinal connectivity.
Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.
Par-complex-dependent cell polarity can be cell-autonomously conferred to non-polar Drosophila S2 cells, unveiling temporal patterns toward the cortical localization of Par-complex aggregates that include a meshwork containing unit segments.
Forward genetics and super-resolution microscopy identifies ZitP as a conserved multifunctional regulator that accumulates at both cell extremities in distinct macromolecular structures to perform different functions in the asymmetric model bacterium Caulobacter crescentus.
Mammalian neural stem cells specifically regulate a subset of astral microtubules to govern the subtle changes in spindle orientation that underlie symmetric vs asymmetric cell division during embryonic cortical neurogenesis.
Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.
Nf1 is required during early, but not late, cerebellar development to facilitate neuronal lamination, providing a potential therapeutic prevention strategy for NF1-associated developmental abnormalities.