Peripheral retinal input transiently amplifies information transmission from ganglion cells, dynamically allocating the resources of neural activity to times of expected high information content.
Nonlinear receptive field subunits in retinal ganglion cells are isolated and characterized by clustering spike-triggered stimuli, and validated on population responses to naturalistic and novel closed loop stimuli.
Cassandra L Hays, Asia L Sladek ... Wallace B Thoreson
To improve the reliability of transmitting small single-photon voltage responses, rod photoreceptor cells release synaptic vesicles in regularly timed multivesicular events that are exquisitely sensitive to small voltage changes.
Ankita Ravi Vaswani, Beatrice Weykopf ... Sandra Blaess
The first comprehensive insight into speed, trajectory and morphology profiles of tangentially migrating dopaminergic neurons and the alterations in their migratory behavior in absence of Reelin signaling.
The antimanic action of lithium requires BDNF-TrkB signaling coupled with enhanced dynamin-dependent endocytosis of AMPARs as a potential mechanism underlying the therapeutic effects.
A neuroprotective role mediated by Strip1 maintains retinal ganglion cells during development, which ensures proper positioning of inner retinal neurons and preserves the laminar architecture of the inner retina.
Single-cell tracking and cell-fate simulation suggest that low levels of p53 suppress aneuploid cell formation in unstressed cells and also reveal the dual fate of cells lacking p53 in the presence of p53-proficient cells.
