Eps8, a specific effector of oncogenic signaling, organizes the cortical actin cytoskeleton of cancer cells to promote mechanical properties that favor a newly identified mode of confined, adhesion-independent cell migration.

Fast amoeboid migrating cells require both cofilin-1 and ADF for fast actin turnover at 'leader bleb' necks.

Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach.

The closest living relatives of animals, the choanoflagellates, switch from a flagellate to an amoeboid phenotype under confinement.

Functional analysis of filopodia by specific interference with their formation and distribution reveals a critical role in conferring intracellular polarity and in controlling the dynamic properties of chemokine-guided cell migration in vivo.

Social networks can be the primary risk factor for mumps infection and transmission, regardless of age and vaccination status.

Cortical cholinergic and noradrenergic signaling contains a strong low-frequency component that is distributed across the mouse cortex and is related to the behavioral state of the animal.

Phylogenetic and computational methods reveal that at least two seasonal coronaviruses are evolving adaptively in the region of the viral spike protein exposed to the human humoral immune system.

A pervasive mutation in the Spike protein of the coronavirus that causes COVID-19 results in virions that are up to eightfold more infectious.

Epithelial cells utilize a covering sheath of motile cells to migrate in confinement.