6,436 results found
    1. Cell Biology
    2. Neuroscience

    Short and long sleeping mutants reveal links between sleep and macroautophagy

    Joseph L Bedont, Hirofumi Toda ... Amita Sehgal
    Unbiased and targeted genetic approaches reveal a link between sleep and autophagy that could be relevant for sleep function, and for understanding pathological consequences of chronic sleep loss.
    1. Neuroscience

    Judging the difficulty of perceptual decisions

    Anne Löffler, Ariel Zylberberg ... Daniel M Wolpert
    Deciding which of two perceptual decisions is more difficult involves sequential sampling processes that terminate when the difference in accumulated evidence for each decision exceeds a threshold.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Complementary shifts in photoreceptor spectral tuning unlock the full adaptive potential of ultraviolet vision in birds

    Matthew B Toomey, Olle Lind ... Joseph C Corbo
    Birds that see ultraviolet light tune the sensitivity of their short-wavelength photoreceptors with colored filters to maximize the number of colors they can see.
    1. Ecology

    Climate-driven deoxygenation elevates fishing vulnerability for the ocean's widest ranging shark

    Marisa Vedor, Nuno Queiroz ... David W Sims
    Habitats of satellite-tracked blue sharks were shifted surfaceward by an oxygen minimum zone (OMZ) at depth thereby increasing their susceptibility to capture by longline fishing focused above the OMZ.
    1. Microbiology and Infectious Disease

    Changes in the genetic requirements for microbial interactions with increasing community complexity

    Manon Morin, Emily C Pierce, Rachel J Dutton
    Analysis of the global genetic requirements and gene expression changes in E. coli in the presence of a simple microbiome revealed pairwise and higher-order interactions, and underlying molecular mechanisms.
    1. Cancer Biology
    2. Cell Biology

    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

    Taylor P Enrico, Wayne Stallaert ... Michael J Emanuele
    The SCF-family of ubiquitin ligases regulates the key cancer proliferation node by controlling the degradation of RB-like tumor suppressor RBL2/p130.
    1. Evolutionary Biology

    Whole genomes from the extinct Xerces Blue butterfly can help identify declining insect species

    Toni de-Dios, Claudia Fontsere ... Carles Lalueza-Fox
    The retrieval of whole genomes from museum specimens from the extinct Xerxes Blue butterfly shows signals of population decline that could be use to identify present-day endangered insect species.
    1. Neuroscience

    Ciliary and rhabdomeric photoreceptor-cell circuits form a spectral depth gauge in marine zooplankton

    Csaba Verasztó, Martin Gühmann ... Gáspár Jékely
    In a zooplankton larva, ciliary and rhabdomeric photoreceptor cells work antagonistically to form a spectral depth gauge.
    1. Neuroscience

    Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'

    James Taniguchi, Riccardo Melani ... Nicolas X Tritsch
    We are writing to comment on the article by Mohebi et al., 2023: we show that blue light alters the fluorescent properties of a genetically-encoded dopamine sensor in a manner that may be misconstrued as phasic dopamine release.
    1. Neuroscience

    Neuronal processing of noxious thermal stimuli mediated by dendritic Ca2+ influx in Drosophila somatosensory neurons

    Shin-Ichiro Terada, Daisuke Matsubara ... Tadao Usui
    Drosophila polymodal nociceptors use precipitous fluctuation of the firing rate, which depends on Ca2+ influx, as a key signal encoding a heat sensation and evoking the robust heat avoidance behavior.

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