Analyses combining genomic and epidemiological data of Mycobacterium bovis, which causes bovine tuberculosis, revealed evidence of transmission within and between cattle and badger populations.
An unbiased screen using various stresses reveals selective mRNA transport into P-bodies, in which mRNAs are either stored or decayed in a process that may promote chronological lifespan in yeast.
Multivesicular bodies deliver long-range retrograde nerve growth factor (NGF) signals and serve as essential signaling and sorting platforms in the cell soma, and multivesicular body (MVB) cargoes dictate their vesicular fate.
Single and double-knockout mouse models for proteins associated with nodes of Ranvier reveal that a paranodal, spectrin-based lateral diffusion barrier is sufficient to cluster Na+ channels at nodes of Ranvier.
“Discontinuous” and “Continuous” migration modes are divergent mesenchymal migration strategies that arise spontaneously in parallel in an equilibrium modulated by cell-matrix attachment and actomyosin contractility.
The RIF1-long and short splice variants show distinct ability to protect cells from replication stress by promoting 53BP1 nuclear bodies, representing the first described functional difference between the two variants.