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Page 2 of 533
Maturation of a central brain flight circuit in
Tarjani Agrawal, Gaiti Hasan
Gene knockdown experiments in fruit fly pupae reveal the role of the signaling molecule 'dFrizzled2' in the development of a neural circuit that helps insects to fly continuously for extended periods.
A size principle for recruitment of
leg motor neurons
Anthony W Azevedo et al.
Motor neurons controlling the leg of the fruit fly exhibit a gradient of physiological and functional properties that correlate with the order in which they fire during behavior.
Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice
Yu Shi, Fanxin Long
Targeted activation of Hedgehog signalling via Gli2 facilitated the reduction of high-fat-diet-induced obesity and improvement of whole-body glucose tolerance and insulin sensitivity in adult mice.
Distinct ipRGC subpopulations mediate light’s acute and circadian effects on body temperature and sleep
Alan C Rupp et al.
Daily fluctuations versus transient perturbations in environmental light influence behavior and physiology through distinct circuits.
Biochemistry and Chemical Biology
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias
Bradford M Stubenhaus et al.
Physiological porphyrin biosynthesis causes photosensitivity in fasted planarians, providing an experimentally tractable animal model of acute porphyrias.
The cation channel TRPA1 tunes mosquito thermotaxis to host temperatures
Román A Corfas, Leslie B Vosshall
Female mosquitoes are exquisitely sensitive to human body heat, and the
gene is required to focus their attraction toward thermal stimuli resembling warm-blooded hosts.
A primal role for the vestibular sense in the development of coordinated locomotion
David E Ehrlich, David Schoppik
Zebrafish use their sense of gravity and their cerebellum to coordinate the fin and body movements that, as they develop, allow them to better maintain balance as they climb.
Preservation of three-dimensional anatomy in phosphatized fossil arthropods enriches evolutionary inference
Achim H Schwermann et al.
X-ray imaging reveals well-preserved internal characters in mineralized arthropods from the Paleogene, urging the reexamination of previously neglected fossil collections.
Quantitative uniqueness of human brain evolution revealed through phylogenetic comparative analysis
Ian F Miller et al.
The exceptionally large size of the human brain is the result of accelerating evolution towards larger brains in hominins, but is not the product of neocortical expansion.
A fitness trade-off between seasons causes multigenerational cycles in phenotype and population size
Gustavo S Betini et al.
Seasonal variation in resources causes opposing episodes of selection on body size, which interact with density dependence to influence population dynamics.
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