Aryeh Solomon, Noa Bossel Ben-Moshe ... Roi Avraham
In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.
miR-335-3p, which targets FOS and inhibits its activation of NFATC1 signaling, is an important regulator for osteoclast function and responsible for the psychological stress-induced osteoporosis.
Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.
Ablation of the G-protein-coupled receptor C3aR1 specifically on macrophages or Kupffer cells does not alter the course of metabolic dysfunction-associated steatotic liver disease in a dietary mouse model.
Miki Kume, Hanako Koguchi-Yoshioka ... Rei Watanabe
Downregulation of Sema4A in keratinocytes induces psoriatic non-lesional features, with its signaling cascades potentially triggering psoriasis and serving as targets for treatment and prevention.
