The differentiation decisions made by pluripotent cells depend on their exposure to appropriate extrinsic signals and also on morphogenetic events that control receptivity to those differentiation cues.
Members of the BMP family of growth factors act as a reiterative code of distinct activities to direct the identities of different classes of sensory neurons in the spinal cord.
A new morphological structure evolved through extreme changes in cell height requires novel connections to an extracellular matrix network, which predates the origin of structure.
New views on the relevance of bone morphogenetic protein signalling fine tuning in the cardiac neural crest cells for the heart outflow tract septation and the formation of the great arteries.
The evolutionarily conserved polarity protein Crumbs links the regulation of cytoskeleton dynamics and cell-cell adhesion with epithelial morphogenesis.
The lens-averted domains of the optic vesicle are reservoirs of neuroretinal cells that flow into the developing optic cup in a process that is critically influenced by BMP signaling.