945 results found
    1. Neuroscience

    Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

    Wankun L Li et al.
    Adult-born neurons in the olfactory bulb allow state-dependent pattern separation of representations of similar odorants.
    1. Neuroscience

    Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb

    Jenelle Wallace et al.
    Adult-born neurons in the olfactory bulb that develop in the absence of microglia have a higher density of small spines but weaker excitatory inputs and reduced responses to sensory stimuli.
    1. Computational and Systems Biology
    2. Plant Biology

    Rapid transporter regulation prevents substrate flow traffic jams in boron transport

    Naoyuki Sotta et al.
    To avoid internal traffic jams of nutrients that they absorb, plants need to swiftly regulate the transporters that take up those nutrients.
    1. Neuroscience

    Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks

    Jia-Min Zhuo et al.
    Adult neurogenesis, although happening at a slow rate in the adult brain, plays an important role in learning and memory and has the ability to powerfully modulate large scale neural networks.
    1. Neuroscience

    Adult-born granule cells mature through two functionally distinct states

    János Brunner et al.
    3-10 weeks old adult-born granule cells provide two temporally overlapping but functionally distinct neuronal cell populations by being sensitive to distinct aspects of their inputs.
    1. Neuroscience

    Opposite regulation of inhibition by adult-born granule cells during implicit versus explicit olfactory learning

    Nathalie Mandairon et al.
    While both implicit and explicit learning augment neurogenesis, adult-born cells differ in their morphology, functional coupling and inhibitory action impacting differentially the olfactory bulb output.
    1. Ecology

    Implications of being born late in the active season for growth, fattening, torpor use, winter survival and fecundity

    Britta Mahlert et al.
    Being born late in the active season is associated with a fast life history in a hibernating species, the garden dormouse (Eliomys quercinus).
    1. Neuroscience

    Silent synapses generate sparse and orthogonal action potential firing in adult-born hippocampal granule cells

    Liyi Li et al.
    Young neurons of the adult hippocampus are synaptically activated by a small group of non-overlapping afferent excitatory fibers, due to high synaptic gain and sparse connectivity, important for sparse and orthogonal coding during hippocampal information processing.
    1. Neuroscience

    Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells

    Yuntao Duan et al.
    Mice that lack the autism susceptibility gene Semaphorin 5A show excess excitatory synapse formation in dentate granule neurons and also altered social behavior, adding to evidence that a surplus of synapses contributes to the behavioral changes observed in autism spectrum disorders.
    1. Computational and Systems Biology
    2. Neuroscience

    T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells

    Marcel Beining et al.
    T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.

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