LSD induces a pattern of changed global brain connectivity characterized by hypo-connectivity in associative areas and hyper-connectivity across sensory and somatomotor areas that is dependent on the serotonin 2A receptor.
White matter connectivity assessed using diffusion MRI allows one to compare whole-brain organization between different animal species in a quantitative fashion, identifying homologous areas and regions of unique specialization.
Many disorders are characterized by underlying abnormalities in network connectivity which, though difficult to address with explicit training procedures, can be directly targeted through covert neurofeedback.
Connectivity network matrices, as estimated with masking or dual regression against group-level parcellations, reflect little or no unique cross-subject information that is not also captured by spatial topographical variability.
Loss of function of the selective autophagy adaptor protein Alfy/Wdfy3 leads to profound wiring defects from the forebrain through to the spinal cord, highlighting the growing importance for macroautophagy in the developing brain.