4,855 results found
    1. Microbiology and Infectious Disease

    In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

    Kelsey A Haugh et al.
    Retroviruses exploit the lectin, Siglec-1/CD169, expressed on sentinel macrophages to promote infection during multiple routes of transmission.
    1. Neuroscience

    Information flow, cell types and stereotypy in a full olfactory connectome

    Philipp Schlegel et al.
    Synaptic resolution analysis of a full olfactory connectome reveals lateralised circuits, convergence of innate and learned pathways, and shows that homologous neurons are highly stereotyped within and across brains.
    1. Neuroscience

    Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex

    Filippo Ghezzi et al.
    A combined developmental genetics, electrophysiology, and optical approach identify two distinct and dynamic components of the developing neuronal circuit that relay and interpret thalamic input in primary sensory neocortex.
    1. Computational and Systems Biology

    The structural connectome constrains fast brain dynamics

    Pierpaolo Sorrentino et al.
    The fast spreading of neural activity across the brain has a complex structure, imposed by the white-matter bundles.
    1. Neuroscience

    Distinct signatures of calcium activity in brain mural cells

    Chaim Glück et al.
    Increases of extracellular potassium silence capillary pericyte calcium signaling, suggesting a participation of capillary pericytes in the potassium-mediated neurovascular communication.
    1. Neuroscience

    Preserved sensory processing but hampered conflict detection when stimulus input is task-irrelevant

    Stijn Adriaan Nuiten et al.
    When all features of conflicting sensory input are task-irrelevant, the brain can still process its sensory information, whereas conflict detection requires that minimally one stimulus feature is task-relevant or associated with a response.
    1. Cell Biology
    2. Neuroscience

    Miro1-dependent mitochondrial dynamics in parvalbumin interneurons

    Georgina Kontou et al.
    Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.
    1. Computational and Systems Biology
    2. Neuroscience

    Mice in a labyrinth show rapid learning, sudden insight, and efficient exploration

    Matthew Rosenberg et al.
    Mice exploring a labyrinth freely for the first time learn a complex action sequence after a handful of rewards, exhibiting a learning rate 1000-fold higher than in commonly-used paradigms.
    1. Cell Biology
    2. Neuroscience

    Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

    Kirsty J McMillan et al.
    An unbiased proteomic approach identifies a new regulator of AMPA receptor trafficking providing additional insight into synaptic transmission and plasticity.
    1. Computational and Systems Biology
    2. Neuroscience

    Place-cell capacity and volatility with grid-like inputs

    Man Yi Yim et al.
    A very large number of place-field maps can be robustly learned by association of external cues with the grid-driven response, however plasticity in the grid-cell inputs renders the place-cell responses volatile.

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