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    1. Neuroscience

    Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus

    Francois M Lambert, Laura Cardoit ... Didier Le Ray
    Molecular labeling, electrophysiology and calcium imaging have revealed a novel switching of neurotransmitter at the frog neuromuscular junction where motoneurons transiently release glutamate before acetylcholine at synapses on developing hindlimb muscles at the onset of metamorphosis.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2

    Yunjeong Lee, In Seo Yeo ... Mi-Ryoung Song
    Isl2 orchestrates specific hindlimb motor pool arrangement, guaranteeing accurate motor control and sensorimotor circuit functionality.
    1. Developmental Biology

    Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

    Marketa Kaucka, Tomas Zikmund ... Igor Adameyko
    The clonal oriented cell dynamics enables directional expansion and accurate scaling of sheet-like or rod-like cartilaginous elements and uncouples the mechanisms of elongation from thickness or diameter control.
    1. Neuroscience

    Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

    Han SJ Cheong, Katharina Eichler ... Gwyneth M Card
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    De novo identification of universal cell mechanics gene signatures

    Marta Urbanska, Yan Ge ... Jochen Guck
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner

    Zhuo Guan, Monica C Quiñones-Frías ... J Troy Littleton
    Drosophila synaptotagmin 7 functions to restrict SV availability and release, but does not act as the Ca2+ sensor mediating the asynchronous release and facilitation remaining in synaptotagmin 1 mutants.
    1. Developmental Biology

    Muscle-derived Myoglianin regulates Drosophila imaginal disc growth

    Ambuj Upadhyay, Aidan J Peterson ... Michael B O'Connor
    A Drosophila myostatin-like factor provides an extrinsic signal produced by muscles that regulates Drosophila appendage development.
    1. Neuroscience

    Magnetic stimulation allows focal activation of the mouse cochlea

    Jae-Ik Lee, Richard Seist ... Shelley Fried
    Coil-based CIs have the potential to enhance the quality of restored hearing for people with severe to profound hearing loss.
    1. Neuroscience

    The recovery of standing and locomotion after spinal cord injury does not require task-specific training

    Jonathan Harnie, Adam Doelman ... Alain Frigon
    Restoring locomotion after complete spinal cord injury does not require locomotor training, only the return of sufficient excitability within neurons of the spinal cord.
    1. Neuroscience

    Mesoscopic-scale functional networks in the primate amygdala

    Jeremiah K Morrow, Michael X Cohen, Katalin M Gothard
    Multivariate data decomposition applied to local field potentials recorded from the primate amygdala revealed simultaneously active and functionally distinct networks, defined by anatomical boundaries between the nuclei.