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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing

    Wenbo Liu, Xukun Lu ... Jianqiao Liu
    SRSF10 directly binds genes functioning in spermatogonia and regulates their alternative splicing, the defect of which can lead to progenitor expansion failure.
    1. Cell Biology

    TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

    Fernando R Balestra, Andrés Domínguez-Calvo ... Pierre Gönczy
    TRIM37 prevents the formation of centriolar protein assemblies through an atypical de novo assembly pathway that would otherwise threaten genome integrity.
    1. Developmental Biology
    2. Neuroscience

    Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

    Sung-Ho Huh, Mark E Warchol, David M Ornitz
    Otic epithelial Fibroblast Growth Factors control the number of cochlear sensory progenitor cells through an FGF responsive periotic mesenchyme.
    1. Neuroscience

    Across-species differences in pitch perception are consistent with differences in cochlear filtering

    Kerry MM Walker, Ray Gonzalez ... Andrew J King
    Humans and other animals have different strategies for extracting the pitch of sounds, potentially driven by the species-specific frequency selectivity of the ear.
    1. Evolutionary Biology

    The structure of species discrimination signals across a primate radiation

    Sandra Winters, William L Allen, James P Higham
    Machine learning and experimental tests of receiver bias identify signal components critical to correct species classification in guenons, linking face pattern diversity to selection for species discrimination.
    1. Ecology
    2. Neuroscience

    Patterns of call communication between group-housed zebra finches change during the breeding cycle

    Lisa F Gill, Wolfgang Goymann ... Manfred Gahr
    Call-based vocal communication of individually recorded zebra finches changes in social groups across reproductive stages and is related with successful egg laying.
    1. Structural Biology and Molecular Biophysics

    Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating

    Marina A Kasimova, Debanjan Tewari ... Baron Chanda
    The gating polarity of a voltage-gated ion channel is primarily determined by turn propensity of residues at a critical position in the middle of the S4 voltage-sensing helix.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin

    Sohum Mehta, Nwe-Nwe Aye-Han ... Jin Zhang
    The ability of calcium waves to exert different effects on calcineurin activity depending on subcellular location is mediated by the distribution of calmodulin.
    1. Cell Biology
    2. Developmental Biology

    Ciliary length regulation by intraflagellar transport in zebrafish

    Yi Sun, Zhe Chen ... Chengtian Zhao
    The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.
    Version of Record
    Short Report
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    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors

    Silvia Peluso, Adam Douglas ... Robert E Hill
    FGF signalling is responsible for priming the developmental enhancer ZRS across the distal limb mesenchyme during development, allowing ETS factors to modulate its activity through balancing histone acetylation.