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Rapid increases in the brain’s level of alertness, or arousal, contribute to variability in decision making by reducing existing biases.

Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.

Computational modeling motivated by recent experiments clarifies biophysical mechanisms generating the rhythm and amplitude of breathing at the level of neurons and brain circuits in mammals.

SLC7A8 a neutral amino acid transporter has a key role in the maintenance of hearing during aging and its absence causes early onset of hearing loss.

High-resolution imaging shows that the different columns of the human periaqueductal gray play differential roles in the response to a respiratory threat.

Building on previous work (Wang et al., 2014), we use a combination of genetic, electrophysiology and laser ablation approaches to identify a developmentally defined population of neurons that are a significant source of clinically relevant inspiratory drive to XII motoneurons.

Action potentials propagating in axon bundles with bifurcating and terminating fibers cause strong and far-reaching extracellular potentials.

Astrocytes modulate neuronal networks during hypercapnia, introducing a novel gliotransmitter pathway where prostaglandin E2 regulates breathing.

Developmental hearing loss causes perceptual deficits that are best explained by degraded auditory cortical encoding that is recorded during task performance.

Building on previous work (Faull et al, 2016), it shown that the different connectivity profiles of the individual columns of the human periaqueductal gray support their proposed roles in human threat behaviours, such as freezing or fight/flight.