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Parallel chemical and physiological profiling of conspecific chemosensory communication in mice identifies both common and unique strategies for vomeronasal signaling of sex and strain.

Spontaneous fusion of vesicles at synapses is regulated independently of fusion triggered by action potentials, adding to evidence that the two types of fusion have distinct functions.

An aspartyl protease is essential for the lytic cycle of Toxoplasma gondii and is involved in the maturation of proteins critical for invasion and egress, and it can be targeted selectively with an ethylamine scaffold based peptidomimetic inhibitor.

Longitudinal calcium imaging in awake mice after stroke suggests impairments in neuronal activity, functional connectivity, and neural assembly architecture is transient and limited to cortex immediately adjacent to the stroke.

Latrophilin-2 G protein coupling is required in axons but not target neurons for neural circuit assembly in the mouse hippocampus.

Activation of a population of glutamatergic neurons in supramammillary nucleus enhances active coping behaviors in response to threats, offering new insights for therapeutic strategies against anxiety and mood disorders.

Gene expression was analyzed in hippocampal principal cells, enabling cellular phenotyping and revealing novel organizational principles; complementing this, a publicly available website is released to provide outside analysis and visualization of hippocampal RNA-seq data in an accessible fashion.

The combination of short-term and long-term plasticity enables hippocampus to learn goal-directed paths through replay in a reversed order.

Structure–function studies on the synaptic vesicle release protein syntaxin-1 identified structural motifs on the surface of the SNARE complex controlling vesicle priming and spontaneous release unique for synaptic signaling.

Fruit flies have special neurons in their pharynx with ionotropic receptors to prevent consuming too much salt, which was confirmed using a variety of behavioral and physiological assays.