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    1. Neuroscience

    Synaptic connectivity to L2/3 of primary visual cortex measured by two-photon optogenetic stimulation

    Travis A Hage, Alice Bosma-Moody ... Gabe J Murphy
    A combination of multicellular recording and optogenetic photostimulation was used to deeply characterize the spatial profiles and effective strengths of intralaminar and translaminar synaptic connections from genetically defined neuronal populations in the visual cortex of adult mouse.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon, Sarah E Lower ... Jing-Ke Weng
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Neuroscience

    Neural circuit mechanisms for steering control in walking Drosophila

    Aleksandr Rayshubskiy, Stephen L Holtz ... Rachel I Wilson
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Nuclear bodies protect phase separated proteins from degradation in stressed proteome

    Kwan Ho Jung, Jiarui Sun ... Xin Zhang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Microbiology and Infectious Disease

    Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

    Vivian Salgueiro, Jorge Bertol ... Rafael Prados-Rosales
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    Information gain at the onset of habituation to repeated stimuli

    Giorgio Nicoletti, Matteo Bruzzone ... Daniel Maria Busiello
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Visual information is broadcast among cortical areas in discrete channels

    Yiyi Yu, Jeffery N Stirman ... Spencer LaVere Smith
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making

    Mickaël Degoulet, Louis-Matis Willem ... Patrick A Pintus
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System

    Bowen Yu, Penghai Li ... Yaoyao Hao
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    A parameterized two-domain thermodynamic model explains diverse mutational effects on protein allostery

    Zhuang Liu, Thomas G Gillis ... Qiang Cui
    A combined theoretical and experimental study revealed the mechanistic and structural basis of mutational effects on allostery and provided insights into the intrinsic connection of intra- and inter-domain properties.
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