7,466 results found
    1. Cell Biology
    2. Computational and Systems Biology

    Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

    John M Ankers et al.
    Cell imaging and mathematical modelling show reciprocal cross-regulation between inflammatory signalling and cell cycle timing, which is mediated through functional interactions between NF-B and E2F proteins.
    1. Cancer Biology
    2. Cell Biology

    A versatile system to record cell-cell interactions

    Rui Tang et al.
    A novel reporter system that employs cell surface antigen-nanobody pairing enables physical interaction-dependent labeling and functional modification between diverse cell types.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Defining host–pathogen interactions employing an artificial intelligence workflow

    Daniel Fisch et al.
    The application of deep learning fills a major gap in host–pathogen research providing for unbiased, multi-module high-throughput image analysis.
    1. Cell Biology
    2. Computational and Systems Biology

    Decoupling global biases and local interactions between cell biological variables

    Assaf Zaritsky et al.
    DeBias is a generic method to decompose and quantify the confounding, global factors and direct interactions of pairwise interacting variables.
    1. Cancer Biology

    MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

    Tessa M Popay et al.
    Interaction of oncoprotein transcription factor MYC with chromatin-associated protein host cell factor–1 controls expression of genes important for ribosome biogenesis and mitochondrial vigor, loss of which promotes tumor regression.
    1. Developmental Biology

    Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

    Octavian Voiculescu et al.
    A combination of two local cell interactions, intercalation and ingression amplified by a community-effect, is sufficient to explain the global movements of amniote gastrulation.
    1. Microbiology and Infectious Disease

    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

    Malgorzata Broncel et al.
    Myristoylation of a secreted protein, identified in a global myristoylation analysis of the eukaryotic parasite Toxoplasma gondii, is important for host cell invasion.
    1. Microbiology and Infectious Disease

    Differential interaction forces govern bacterial sorting in early biofilms

    Enno R Oldewurtel et al.
    Differential physical interactions between bacteria in mixed microcolonies trigger cell sorting.
    1. Cell Biology

    Synthetic protein interactions reveal a functional map of the cell

    Lisa K Berry et al.
    Forcing protein associations across the proteome reveals the cell's tolerance for diverse protein interactions and reveals the interactions that affect growth.
    1. Neuroscience

    Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations

    Andrew M Garrett et al.
    Mammalian Dscams require different intracellular interactions in different cell types during neural circuit formation to promote self-avoidance.

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