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Biochemistry and Chemical Biology
Protein sequences bound to mineral surfaces persist into deep time
Beatrice Demarchi et al.
A chemically unstable ostrich eggshell peptide survives for at least 3.8 million years at the equator, stabilized by strong mineral interactions.
Physics of Living Systems
Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends
Andrea Serra-Marques et al.
The function and distribution of kinesin motors on exocytotic vesicles is dissected and visualized through a combination of gene knockout experiments, high-resolution microscopy and advanced data analysis.
Lissencephaly-1 is a context-dependent regulator of the human dynein complex
Janina Baumbach et al.
An in vitro reconstitution approach reveals context-dependent roles of Lissencephaly-1 in the regulation of dynein-dynactin behaviour on dynamic microtubules.
Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity
Liu He et al.
UNC119 complexes the microtubule binding CRMP to the cortical Ankyrin to immobilize the microtubule cytoskeleton in
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