Inhaled fine particulate matters impair immune defense to accelerate tumorigenesis by pulling the strings of interstitial collagen in lung tissue.

Natural antibodies play a fundamental role in anti-cancer immunity.

A new, high-throughput in vivo MHC-I peptide minigene library platform shows that the naive immune system cannot eliminate cells presenting immunogenic antigens found at low frequencies within a growing tumor.

Mucosal-associated invariant T cells, an emerging member of the innate-like T cells abundant in humans bridging the innate and the adaptive immunity, could be exploited as a novel tool for cancer immunotherapy through cell reprogramming.

Prdm1 (BLIMP1) promotes liver Group 1 ILCs cancer surveillance and preserves functional heterogeneity.

New roles in anti-tumour immunity for the adhesion protein Kindlin-1 via regulation of cytokine secretion and T cell regulation.

Theoretical modeling reveals how stochastic optimal cancer immune evasion via antigen downregulation gives rise to diverse post-escape cancer antigenic profiles in a manner dependent on the immune microenvironment.

A time-gated model is proposed to reconcile the transient vs. persistent biological activities of cellular senescence, in which 'time' seems to be the main orchestrator of the beneficial vs. detrimental effects of the senescent programme.

Antitumor (natural killer) NK cell responses are negatively regulated by interactions between NK cells and endogenous NKG2D ligands constitutively expressed on lymph node endothelial cells and super-induced on tumor-associated endothelium.