12 results found
    1. Neuroscience

    Sex Difference: What does cannabis do to the brain before birth?

    Stefano Musardo, Camilla Bellone
    Being exposed to cannabinoids in the womb has different consequences for male and female rats. .
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    1. Neuroscience

    Sex-dependent effects of in utero cannabinoid exposure on cortical function

    Anissa Bara et al.
    Adult male, but not female, rats showed altered neuronal function, inhibited synaptic plasticity and diminished social behavior following cannabinoid exposure during gestation in a model of cannabis use during pregnancy.
    1. Developmental Biology
    2. Neuroscience

    Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth

    Alexandre B Roland et al.
    Cannabinoids inhibit neuronal expansion and growth through the rapid contraction of actomyosin.
    1. Genetics and Genomics
    2. Neuroscience

    Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1

    Alexandra M Stafford et al.
    The trace amine-associated receptor 1 gene has a causal role in methamphetamine intake and thermal response, and interacts with the mu-opioid receptor gene in its methamphetamine addiction-related effects.
    1. Genetics and Genomics
    2. Neuroscience

    A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia

    Nathan G Skene et al.
    A genetic program controlling brain genes across the lifespan specifies a calendar of changes in cells, synapses and behavioural genes thereby timing the onset of mental illnesses which arise in young adults.
    1. Neuroscience

    Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells

    Loïs S Miraucourt et al.
    Endocannabinoid activation of the CB1 receptor on retinal ganglion cells in the eye results in enhanced excitability and responsiveness to visual stimulation through a novel mechanism involving intracellular chloride regulation.
    1. Neuroscience

    The relationship between spatial configuration and functional connectivity of brain regions

    Janine Diane Bijsterbosch et al.
    Connectivity network matrices, as estimated with masking or dual regression against group-level parcellations, reflect little or no unique cross-subject information that is not also captured by spatial topographical variability.
  1. October 2014

    Episode 15: October 2014

    In this episode we hear about influenza pandemics, eating too much, cannabis and the brain, HIV cure research, and the evolution of sea squirts.
    1. Cancer Biology

    Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

    Andrea Strakova et al.
    Genetics of a canine transmissible tumour show how the world’s oldest cancer “metastasised” through the global dog population – and captured, maintained and rearranged its mitochondrial DNA along the way.
    1. Neuroscience

    p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus

    Shuting Xia et al.
    PAK1 regulates inhibitory synaptic transmission in mice through a cyclooxygenase-2 dependent restriction in tonic, but not phasic, secretion of endocannabinoids.

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