Adult male, but not female, rats showed altered neuronal function, inhibited synaptic plasticity and diminished social behavior following cannabinoid exposure during gestation in a model of cannabis use during pregnancy.
The trace amine-associated receptor 1 gene has a causal role in methamphetamine intake and thermal response, and interacts with the mu-opioid receptor gene in its methamphetamine addiction-related effects.
A genetic program controlling brain genes across the lifespan specifies a calendar of changes in cells, synapses and behavioural genes thereby timing the onset of mental illnesses which arise in young adults.
Endocannabinoid activation of the CB1 receptor on retinal ganglion cells in the eye results in enhanced excitability and responsiveness to visual stimulation through a novel mechanism involving intracellular chloride regulation.
Connectivity network matrices, as estimated with masking or dual regression against group-level parcellations, reflect little or no unique cross-subject information that is not also captured by spatial topographical variability.
Genetics of a canine transmissible tumour show how the world’s oldest cancer “metastasised” through the global dog population – and captured, maintained and rearranged its mitochondrial DNA along the way.
PAK1 regulates inhibitory synaptic transmission in mice through a cyclooxygenase-2 dependent restriction in tonic, but not phasic, secretion of endocannabinoids.
