74 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Na+/K+ pump interacts with the h-current to control bursting activity in central pattern generator neurons of leeches

    Daniel Kueh, William H Barnett ... Ronald L Calabrese
    The dynamic current generated Na+/K+ pump interacts with the h-current to control the bursting activity of oscillator heart interneurons.
    1. Neuroscience

    Regional response to light illuminance across the human hypothalamus

    Islay Campbell, Roya Sharifpour ... Gilles Vandewalle
    Distinct local dynamics of different hypothalamus areas were detected in response to changing illuminance and could contribute to light’s impact on cognition.
    1. Neuroscience

    Robust group- but limited individual-level (longitudinal) reliability and insights into cross-phases response prediction of conditioned fear

    Maren Klingelhöfer-Jens, Mana R Ehlers ... Tina B Lonsdorf
    Reliability and predictability analyses beyond standard measures provide empirically based guidance regarding the design of fear conditioning tasks to assess individual differences and group-level inferences cross-sectionally and longitudinally.
    1. Neuroscience

    The organizational principles of de-differentiated topographic maps in somatosensory cortex

    Peng Liu, Anastasia Chrysidou ... Esther Kuehn
    SI topographic finger maps of older adults show signs of cortical aging but do not show classical hallmarks of cortical de-differentiation.
    1. Neuroscience

    Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules defined by distinct pinceau sizes

    Joy Zhou, Amanda M Brown ... Roy V Sillitoe
    Targeted genetic silencing and reporter labeling reveal that Purkinje cell activity organizes cerebellar basket cells into zonal modules based on the sizes of their projections.
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Light-driven synchronization of optogenetic clocks

    Maria Cristina Cannarsa, Filippo Liguori ... Roberto Di Leonardo
    Introducing the optorepressilator, a synthetic genetic oscillator that can be synchronized, entrained, and detuned by green light to precisely control periodic gene expression in single cells or entire bacterial populations.
    1. Structural Biology and Molecular Biophysics

    The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels

    Alessandro Porro, Andrea Saponaro ... Anna Moroni
    Experimental and computational approaches reveal how ligand binding is coupled to voltage sensing in a HCN channels.
    1. Medicine
    2. Neuroscience

    The importance of individual beliefs in assessing treatment efficacy

    Luisa Fassi, Shachar Hochman ... Roi Cohen Kadosh
    Participants' subjective beliefs about the treatment received in an intervention study can explain variability in mental health symptoms and cognition.
    1. Neuroscience

    The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

    Sandra P Cárdenas-García, Sundas Ijaz, Alberto E Pereda
    Anatomical study reveals a new perspective on the definition of an electrical synapse where, in addition to the communicating role of gap junctions, additional cellular structures might be involved in the support and regulation of these intercellular channels.

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