The first complete 3D structures of mouse cholinergic neurons reveal the length and complexity of their axons, while calculations suggest that equivalent axons in the human brain are approximately than 100 meters long.

Short peptide motifs can confer specificity to developmental networks by inhibiting protein–protein interactions.

Mice deficient in the TRPM6 channel suffer from impaired prenatal development, shortened lifespan, growth deficit and disturbed energy balance due to a defect in epithelial Mg²⁺ uptake, thus highlighting a pivotal role of TRPM6 in organismal Mg²⁺ homeostasis.

Individual nonmuscle myosin 2 filaments in cells may differ their mechanical and kinetic properties depending on the myosin paralog composition giving the cells a mechanism for fine tuning the output of a given nonmuscle myosin filament.

The transcription factor HAND2 evolved uterine expression during the origins of pregnancy and may be important for maternal-fetal immune signaling and parturition.

A retrotransposon-derived recombination event in inbred mice gives rise to an epiallele and tissue-specific phenotypes.

Mice doubly deficient for Naa10 and Naa12 display embryonic lethality, with both enzymes compensating for each other with amino-terminal acetylation of proteins in mouse development.

While Trypanosoma congolense is mostly known to cause a chronic wasting disease in animals, a new mouse model shows that acute cerebral trypanosomiasis is triggered by parasite sequestration and infiltration of T helper cells in the brain parenchyma.

Dnajb6 is identified as a novel sick sinus syndrome causative gene that exhibits a unique expression pattern within a subpopulation of sinus node pacemaker cells.

Precise dosage of the imprinted H19 and Igf2 genes is critical for normal embryonic development, especially related to the cardiac-placental axis.