Sequence changes in the pneumococcal genome explain most of the variability in duration of asymptomatic carriage with serotype, antibiotic resistance and prophage accounting for the largest effects.

Being able to take up DNA from their environment might allow pneumococcal bacteria to colonize the human nose and throat for longer periods of time.

A set of paintings by Gustav Klimt highlights ongoing tensions in the relationships between art, science and society.

Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?

The proper development of the vocal cords requires embryos to contain a certain number of progenitor cells, and mutations that lead to an overflow of cells can cause malformations of the voice box.

Ending the TB epidemic requires scaling up access to new TB tools so that they can benefit the patients in low- and middle-income countries that need them the most.

Autosomal dominant IRF4 deficiency is the first genetic etiology of Whipple's disease, a very rare chronic condition following a rather common infection by Tropheryma whipplei.

Analysis of aging yeast cells using the in-vivo roGFP2-based probe reveals redox-dependent heterogeneity, reflected in a bi-modal distribution of the oxidation status, differential growth and replication, as well as distinct proteomic and transcriptomic profiles.

Structure, dynamics, and mutation of a gamete fusion protein and comparisons to viral homologues suggest that after trimerization the domain bearing the membrane-inserting fusion loops can pivot with respect to the trimer 3-fold axis.

Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.