52 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Epidemiological dynamics of Ebola outbreaks

    Thomas House
    The pattern of past Ebola outbreaks is indicative of an effective reproductive ratio of less than 1, which can lead to the generation of a range of outbreak sizes consistent with the scale of the ongoing epidemic.
    1. Epidemiology and Global Health
    2. Medicine

    Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

    ISARIC Clinical Characterisation Group, Matthew D Hall ... Piero L Olliaro
    Patient outcomes, and the time spent by patients during hospital admission, showed considerable variation over the first year of the COVID-19 pandemic.
    1. Epidemiology and Global Health

    COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)

    Wan Yang, Jeffrey L Shaman
    Model-inference reconstructed SARS-CoV-2 transmission dynamics in South Africa during March 2020 to February 2022, and quantified the immune erosion potential and transmissibility of three major variants (Beta, Delta, and Omicron), highlighting their common characteristics and the need for more proactive preparedness.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Future COVID19 surges prediction based on SARS-CoV-2 mutations surveillance

    Fares Z Najar, Evan Linde ... Pratul K Agarwal
    A real-time genomic surveillance approach based on mutation analysis of SARS-CoV-2 proteins has enabled a priori prediction of surge in number of COVID19 infection cases, including those already observed in July and September 2022.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

    Bronner P Gonçalves, Matthew Hall ... ISARIC Clinical Characterisation Group
    Combined analyses of publicly available population-level variant data and detailed individual-level clinical data can be used to quantify the clinical impact of new SARS-CoV-2 variants in different settings.
    1. Epidemiology and Global Health

    Early analysis of the Australian COVID-19 epidemic

    David J Price, Freya M Shearer ... James M McCaw
    An analysis of Australian case data demonstrates how the combined strategy of border measures, case targeted interventions, and social distancing effectively contained the first epidemic wave of COVID-19.
    1. Epidemiology and Global Health

    Lives saved with vaccination for 10 pathogens across 112 countries in a pre-COVID-19 world

    Jaspreet Toor, Susy Echeverria-Londono ... Katy AM Gaythorpe
    Vaccination activities that occurred before the COVID-19 pandemic, 2000-2019, are estimated to avert 50 million deaths, highlighting the enormous benefits of continued and improving vaccination.
    1. Epidemiology and Global Health

    Collider bias and the apparent protective effect of glucose-6-phosphate dehydrogenase deficiency on cerebral malaria

    James A Watson, Stije J Leopold ... Nicholas J White
    Selection bias, also known as collider bias, likely explains the apparent protective effect of G6PD deficiency against cerebral falciparum malaria.
    1. Epidemiology and Global Health

    Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study

    Wilson Suraweera, David Warrell ... Prabhat Jha
    Prevention and antivenom treatment could reduce snakebite deaths, which killed 1.2 million Indians from 2000-2019, about 70% of which occurred in eight states, and half during four rainy months.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: SARS-CoV-2 (COVID-19) by the numbers

    Yinon M Bar-On, Avi Flamholz ... Ron Milo
    Key numbers about the biology of the SARS-CoV-2 virus and the infection of a single human host by the virus have been compiled from the peer-reviewed literature.

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