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Page 2 of 105
    1. Neuroscience

    A resource for the Drosophila antennal lobe provided by the connectome of glomerulus VA1v

    Jane Anne Horne, Carlie Langille ... Ian A Meinertzhagen
    FIB-SEM is used to identify comprehensively and reconstruct 192 neurons and their complete connectome for glomerulus VA1v of the Drosophila antennal lobe, in particular to reconstruct its local interneurons.
    1. Evolutionary Biology

    Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila

    Berra Erkosar, Cindy Dupuis ... Tadeusz J Kawecki
    Juvenile and adult metabolism are constrained from evolving independently from each other even in a species that lacks developmental continuity between juvenile and adult organs.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao, Stéphane U Rigaud ... Yohanns Bellaïche
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.
    1. Neuroscience

    Brain-wide analysis of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury

    Zimei Wang, Adam Romanski ... Murray G Blackmore
    Three-dimensional imaging and automated, brain-wide cell counting yield new insight into the diversity of neurons that connect the brain to the spinal cord and their different sensitivity to spinal cord damage.
    1. Cell Biology

    Metabolic regulation of misfolded protein import into mitochondria

    Yuhao Wang, Linhao Ruan ... Rong Li
    The conserved AMP-activated protein kinase inhibits mitochondrial import of misfolded proteins and helps preserve mitochondrial and cellular fitness under proteotoxic stress.
    1. Neuroscience

    A transformation from temporal to ensemble coding in a model of piriform cortex

    Merav Stern, Kevin A Bolding ... Kevin M Franks
    A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
    1. Neuroscience

    Independent and interacting value systems for reward and information in the human brain

    Irene Cogliati Dezza, Axel Cleeremans, William H Alexander
    Reward and information are independently optimized in the human prefrontal cortex, while their signals combine in subcortical regions.
    1. Chromosomes and Gene Expression

    Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan

    Zheng Hu, Bo Xia ... Jessica K Tyler
    Activation of the stress response pathway in young cells extends replicative lifespan, not by reducing global protein synthesis per se, but by Gcn4-mediated autophagy induction.
    1. Neuroscience

    Unsupervised changes in core object recognition behavior are predicted by neural plasticity in inferior temporal cortex

    Xiaoxuan Jia, Ha Hong, James J DiCarlo
    Temporal continuity-induced plasticity in individual neurons of inferior temporal cortex builds neural representations that underlie robust core object recognition behavior.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-resolution species assignment of Anopheles mosquitoes using k-mer distances on targeted sequences

    Marilou Boddé, Alex Makunin ... Mara KN Lawniczak
    Large-scale monitoring of Anopheles populations benefits from a robust and accurate species identification and plasmodium detection method that is applicable to the entire genus.