John W Biddle, Rosa Martinez-Corral ... Jeremy Gunawardena
The effective higher-order binding cooperativities arising from an ensemble of dynamically interchanging conformations are identified and shown to fully describe integration of binding information at thermodynamic equilibrium.
Midbrain dopaminergic neurons and a cortex-like structure called the arcopallium form part of a circuit that enables young songbirds to compare their own song with a template stored in memory, and use any discrepancies to improve their performance.
Jeffrey C Erlich, Bingni W Brunton ... Carlos D Brody
Quantitative modeling of inactivations shows the prefrontal cortex (but not parietal cortex) of the rat is obligatory for decisions guided by evidence accumulating longer than 240 ms.
Rita de Cassia Pessotti, Bridget L Hansen ... Matthew F Traxler
The widespread occurrence of metabolically active streptomycetes in Odontotaenius disjunctus beetle frass may insulate their galleries against pathogenic fungal invasion through the production of diverse antimicrobial specialized metabolites.
Konstantinos Tsetsos, Valentin Wyart ... Christopher Summerfield
A striking dissociation exists in the medial prefrontal cortex, with different brain regions responding to value when commitments are deferred to the future and when prospects are judged to be undesirable.
The physical interaction network encoded in the multi-domain protein native structure handles the trade-off between the fast, stable folding and the efficient, reliable function.
Hand somatotopy can be preserved in the primary somatosensory cortex of tetraplegic patients, despite the absence of sensorimotor function and periphery-brain communication, but deteriorates over years after injury.
Tobias Navarro Schröder, Koen V Haak ... Christian F Doeller
By employing high-field fMRI and taking advantage of well-known global connectivity fingerprints and sensitivity to spatial and non-spatial information, it is shown that the entorhinal cortex is primarily divided into anterior and posterior subregions.