1,918 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Evolving interpretable plasticity for spiking networks

    Jakob Jordan, Maximilian Schmidt ... Mihai A Petrovici
    Artificial evolution discovers biophysically plausible plasticity rules for spiking networks that perform competitively with and even outperform labor-intensive human-designed models in various learning scenarios, while providing new views on experimental data.
    1. Ecology
    2. Epidemiology and Global Health

    Using mobile phones as acoustic sensors for high-throughput mosquito surveillance

    Haripriya Mukundarajan, Felix Jan Hein Hol ... Manu Prakash
    Mobile phones can accurately capture sound recordings from mosquito wingbeats with species-specific frequencies, together with metadata about the recording time, location and conditions, to enable rapid low-cost mosquito surveillance using a citizen-science approach.
    1. Genetics and Genomics

    A confinable home-and-rescue gene drive for population modification

    Nikolay P Kandul, Junru Liu ... Omar S Akbari
    Generation of a home-and-rescue gene drive targeting an essential gene reveals confinable population modification.
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Emergence and evolution of an interaction between intrinsically disordered proteins

    Greta Hultqvist, Emma Åberg ... Per Jemth
    The resurrection of ancient ancestral intrinsically disordered proteins reveals the evolution of a protein-protein interaction in molecular detail.
    1. Biochemistry and Chemical Biology

    Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning

    Zhe Zhang, Xu Hong ... Jian Zhan
    The minimal twister sister (TS)-like self-cleaving ribozymes, revealed by deep mutational scanning, represent some of the very few human/primate ribozymes.
    1. Genetics and Genomics

    Human genetic analyses of organelles highlight the nucleus in age-related trait heritability

    Rahul Gupta, Konrad J Karczewski ... Vamsi K Mootha
    Although cellular organelles show a functional deterioration in aging, genetic loci associated with common age-associated disease instead nominate nuclear transcription factors across several age-related diseases.
    1. Neuroscience

    Vocal development in a Waddington landscape

    Yayoi Teramoto, Daniel Y Takahashi ... Asif A Ghazanfar
    An integrated landscape framework shows how the coordinated changes in vocal apparatus, muscles, nervous system, and social interaction together influence the trajectory of vocal development.
    1. Neuroscience

    Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

    Han SJ Cheong, Katharina Eichler ... Gwyneth M Card
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A

    Andrew G Koesters, Mark M Rich, Kathrin L Engisch
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Ecology
    2. Evolutionary Biology

    Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity

    Guilhem Doulcier, Amaury Lambert ... Paul B Rainey
    Artificial selection on communities drives the evolution of interactions and establishes community-level inheritance.

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