8,983 results found
    1. Cell Biology
    2. Ecology

    Quantitative 3D-imaging for cell biology and ecology of environmental microbial eukaryotes

    Sebastien Colin et al.
    Three-dimensional fluorescence imaging of microbial eukaryotes in environmental samples allows accurate automated taxonomic profiling and quantitative data about ultrastructures and interactions of organisms.
    1. Cell Biology
    2. Computational and Systems Biology

    Perturbation biology nominates upstream–downstream drug combinations in RAF inhibitor resistant melanoma cells

    Anil Korkut et al.
    Data-driven systems biology models of signaling predict cellular response to untested perturbations and can nominate drug combinations to overcome drug resistance in cancer cells.
    1. Cell Biology

    Automated cell-type classification in intact tissues by single-cell molecular profiling

    Monica Nagendran et al.
    The ability to rapidly stain for any combination of genes in intact tissue with automated quantification of transcripts in individual cells and spatial re-mapping affords new insights into lung biology, and will greatly accelerate progress in scientific and medical research.
    1. Cell Biology
    2. Neuroscience

    Enhanced FIB-SEM systems for large-volume 3D imaging

    C Shan Xu et al.
    Complete neuronal circuits can be reconstructed, and whole eukaryotic cells imaged, at less than 10 nm isotropic resolution.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic

    Joel M Swenson et al.
    Identification of novel components and regulators of heterochromatin reveals a spatially complex and dynamic organization.
    1. Cell Biology
    2. Developmental Biology

    The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes

    Ying-Ju Chang et al.
    PDZ-RhoGEF controls adipose tissue abundance and whole body metabolism.
    1. Cell Biology
    2. Developmental Biology

    In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

    Fernanda Bajanca et al.
    A multidisciplinary approach was used to translate the mathematical analysis of Dystrophin movements inside muscle cells into the biology of how Dystrophin interacts with the cell membrane.
  1. Equity, Diversity and Inclusion: Alternative strategies for closing the award gap between white and minority ethnic students

    Louise Cramer
    An analysis of the grades awarded to cell biology students at University College London suggests that exams may contribute more to the award gap than coursework in this subject.
    1. Cell Biology
    2. Developmental Biology

    PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix

    S Nahuel Villegas et al.
    A signalling cascade involving PI3K/Akt1 remodels the extra-cellular matrix to achieve atypical cellular responses and control cell fate specification within the embryonic endoderm.
    1. Evolutionary Biology

    Genetic transformation of Spizellomyces punctatus, a resource for studying chytrid biology and evolutionary cell biology

    Edgar M Medina et al.
    Spizellomycespunctatusis a genetically tractable chytrid and model organism for comparative cell biology for understanding evolution of the cell cycle, actin dynamics, and cellularization in fungi and early eukaryotes.

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