2,863 results found
    1. Cell Biology
    2. Developmental Biology

    Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity

    Tim Davies et al.
    Functional molecular analysis of cytokinesis in Caenorhabditis elegans four-cell embryos reveals cell-type-specific variation in the fundamental dependence on a robust f-actin cytoskeleton for successful cell division, mediated by both cell-intrinsic and -extrinsic pathways.
    1. Immunology and Inflammation

    Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection

    Ana-Carolina Oliveira et al.
    Development of a robust Th1 response to infection against an intracellular parasite requires T-cell intrinsic MyD88 signaling, mostly through the upstream IL-18 receptor, for the induction of genes involved in proliferation, cytokine production and migration.
    1. Neuroscience

    Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells

    Ramesh Chittajallu et al.
    Similar to their mouse counterparts, human neurogliaform cells that comprise a specialized from of inhibitory neuron, possess the ability to modulate their intrinsic excitability in response to ongoing network activity.
    1. Neuroscience

    Cell-intrinsic mechanisms of temperature compensation in a grasshopper sensory receptor neuron

    Frederic A Roemschied et al.
    The firing rates of neurons in the grasshopper auditory system are surprisingly robust to changes in temperature, and cell-intrinsic mechanisms are sufficient to explain this temperature insensitivity.
    1. Developmental Biology

    An intrinsic cell cycle timer terminates limb bud outgrowth

    Joseph Pickering et al.
    Size control in limbs is an intrinsically determined process.
    1. Neuroscience

    Kv1.1 contributes to a rapid homeostatic plasticity of intrinsic excitability in CA1 pyramidal neurons in vivo

    Peter James Morgan et al.
    Short, theta-bursts of action potential firing decrease the global excitability of CA1 pyramidal neurons, providing an internal mechanism which could regulate their allocation to memory engrams.
    1. Developmental Biology

    The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

    Qingqing Zhu et al.
    The transcription factor Pou3f1 triggers embryonic stem cells to become neuronal progenitor cells in two ways: by activating the expression of pro-neuronal genes and by blocking external inhibitory signaling cascades.
    1. Neuroscience

    Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms

    Jing Peng et al.
    Transcriptional modules underlie the step-wise construction of neural circuits in the Drosophila visual system.
    1. Cell Biology
    2. Neuroscience

    Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy

    Ori J Lieberman et al.
    In addition to its classic role in synaptic function and plasticity, macroautophagy regulates neuronal intrinsic excitability via degradation of acetylated Kir2 channels to control neurotransmission.
    1. Immunology and Inflammation

    T cell-intrinsic role of IL-6 signaling in primary and memory responses

    Simone A Nish et al.
    IL-6 signaling in T cells controls how sensitive they are to suppression by T regulatory cells, and the way mature to become memory T cells.

Refine your results by:

Type
Research categories