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    1. Microbiology and Infectious Disease

    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

    Malgorzata Broncel et al.
    Myristoylation of a secreted protein, identified in a global myristoylation analysis of the eukaryotic parasite Toxoplasma gondii, is important for host cell invasion.
    1. Microbiology and Infectious Disease

    Differential interaction forces govern bacterial sorting in early biofilms

    Enno R Oldewurtel et al.
    Differential physical interactions between bacteria in mixed microcolonies trigger cell sorting.
    1. Cell Biology

    Synthetic protein interactions reveal a functional map of the cell

    Lisa K Berry et al.
    Forcing protein associations across the proteome reveals the cell's tolerance for diverse protein interactions and reveals the interactions that affect growth.
    1. Neuroscience

    Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations

    Andrew M Garrett et al.
    Mammalian Dscams require different intracellular interactions in different cell types during neural circuit formation to promote self-avoidance.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Nucleolar dynamics and interactions with nucleoplasm in living cells

    Christina M Caragine et al.
    The nucleoplasm surrounding nucleoli in living cells plays a key role in nucleolar dynamics and shape fluctuations in vivo.
    1. Immunology and Inflammation

    Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo

    Robert A Benson et al.
    Temporal availability of antigen presentation by dendritic cells influences the differentiation of follicular helper T (Tfh) cells, which enhances germinal centre responses and induces protective immunity.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A map of directional genetic interactions in a metazoan cell

    Bernd Fischer et al.
    A systematic analysis of gene–gene dependencies using high-throughput imaging of cells detects causal and temporal relationships between genes.
    1. Biochemistry and Chemical Biology

    A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

    Katherine J Susa et al.
    The tetraspanin CD81 uses its ectodomain to export CD19, and the interaction of the two proteins is dynamically regulated by B cell activation state.
    1. Immunology and Inflammation

    A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

    Enas Abu-Shah et al.
    The use of advanced 3D culture systems with engineered quiescent human T-cells, mimicking in vivo cellular dynamics, paves the way to a new era of much needed pre-clinical research tools.
    1. Neuroscience

    Multiple conserved cell adhesion protein interactions mediate neural wiring of a sensory circuit in C. elegans

    Byunghyuk Kim, Scott W Emmons
    The formation of neuronal connectivity of a C. elegans neuron pair is promoted by multiplexed interactions of neural cell adhesion proteins, which are evolutionarily conserved across animal taxa.