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During pathogen infection, natural killer cells require hypoxia-inducible factor-1α for optimal metabolism to prevent apoptosis, thereby reducing viral load and protecting against morbidity.

Myc-dependent induction of amino acid transporter expression in response to T cell receptor activation is essential to enable T cell proteome remodelling upon immune activation.

Metabolic reprogramming in suppressing oxidative stress during TH17 cell differentiation.

Genome-scale metabolic modeling of individual cancer cells and healthy human cells identifies specific and selective metabolic vulnerabilities.

A distinct class of kidney tumors is characterized not by patterns of somatic mutations, but by a distinct metabolism.

TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.

Analysis of the tumor microenvironment reveals that pancreatic tumors experience metabolic stress caused by immune cell degradation of the amino acid arginine, and that pancreatic cancers cope by synthesizing arginine to provide access this amino acid despite low tumor availability.

A eukaryotic cell model overcomes metabolic deficiencies within a complex, self-establishing community that enables the growth-relevant exchange of metabolic intermediates.

Exosomes from cancer-associated fibroblasts enhance the "Warburg effect" in tumors and contain de novo metabolites that can contribute to the entire compendia of central carbon metabolism within cancer cells.

By increasing intracellular cysteine levels, NRF2 engages a tumor suppressive metabolic pathway mediated by cysteine dioxygenase 1.