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Page 3 of 1,179
    1. Stem Cells and Regenerative Medicine

    Skin vasculature and hair follicle cross-talking associated with stem cell activation and tissue homeostasis

    Kefei Nina Li, Prachi Jain ... Tudorita Tumbar
    Hair follicle epithelium and skin vasculature remodeling are coordinated during quiescence, and their cross-talking is associated with the timing of stem cell activation.
    1. Neuroscience

    Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

    Christopher W Mount, Belgin Yalçın ... Michelle Monje
    Oligodendrocyte precursor cells receive brain-wide, circuit-specific intracortical, coritcocortical and thalamocortical synaptic inputs.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones

    Anastasia A Minervina, Mikhail V Pogorelyy ... Aleksandra M Walczak
    High-throughput clonal tracking quantifies intrinsic differences between primary and secondary T cell response.
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Robust model-based analysis of single-particle tracking experiments with Spot-On

    Anders S Hansen, Maxime Woringer ... Xavier Darzacq
    Spot-On is an easy-to-use website that makes a rigorous and bias-corrected modeling framework for analysis of single-molecule tracking experiments available to all.
    1. Cell Biology
    2. Computational and Systems Biology

    Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration

    Alfonso Bolado-Carrancio, Oleksii S Rukhlenko ... Boris N Kholodenko
    Different RhoA and Rac1 dynamics at the cell front and rear are coordinated through periodic GTPase waves, which define the minimal autonomous biochemical machinery necessary and sufficient for cell migration.
    1. Immunology and Inflammation

    Ageing compromises mouse thymus function and remodels epithelial cell differentiation

    Jeanette Baran-Gale, Michael D Morgan ... Georg A Holländer
    Thymus ageing is characterised by both compositional and transcriptional shifts amongst epithelial cells that perturb their differentiation, contribute to organ atrophy and ultimately impair immune function.
    1. Developmental Biology

    Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

    Maaike Welling, Manuel Alexander Mohr ... Periklis Pantazis
    Primed Track is an image analysis tool that allows for computational correction of drifting specimen to enable accurate lineage tracing of mammalian pre-implantation development even for larger imaging time intervals.
    1. Cell Biology
    2. Developmental Biology

    Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process

    Federico Tessadori, Erika Tsingos ... Jeroen Bakkers
    The three-dimensional and asymmetrical transformations undergone by the zebrafish linear heart tube during looping morphogenesis are under the control of cardiac-intrinsic cues.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

    Thomas J Etheridge, Desiree Villahermosa ... Johanne M Murray
    In vivo single-molecule imaging demonstrates that Smc5/6 chromatin association depends on ATP hydrolysis and dsDNA binding, requires Nse6 and is modulated by Brc1 after DNA damage.
    1. Cell Biology

    Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized

    Danielle M Garshott, Elayanambi Sundaramoorthy ... Eric J Bennett
    A hierarchical relationship among highly conserved regulatory ribosomal ubiquitylation events and the presence of antagonistic deubiquitylating enzymes suggests a dynamic ubiquitin code impacts ribosome-associated activities.