Biochemical and genetic tests have revealed that a liver protein called NTCP is a functional receptor for hepatitis B and D viruses, which should lead to an improved understanding of the infections caused by these viruses and assist the development of new intervention strategies.

A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.

Mathematical modeling shows that local populations of the malaria parasite self-organize into a limited number of transient but distinct strains through competition for hosts in immunity space.

A gene that codes for a transcription factor that is involved in lipid and carbohydrate metabolism also has a role in the regulation of circadian rhythms.

Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins.

Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.

The receptor EBI2 is essential for correctly positioning CD4+ dendritic cells in the spleen so that they can present blood-borne antigens to T cells and thereby provoke an antibody response.

Detailed analysis of umbilical cord cells shows that the associations between DNA methylation, gene expression and genetic variation are complex and context-dependent.

The transport of proteins along flagellar microtubules generates the force that enables flagella to propel cells across surfaces.

Synergistic interactions with PI(4,5)P2 and activated Rho1, which are enriched at the apical membrane of tubular organs, facilitate tight apical targeting of the formin Diaphanous.