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Selection for undifferentiated multicellularity emerges in an evolutionary cell-based model because a collective of cells performs chemotaxis better than single cells in a noisy environment.

Barcoded rabies virus tracing combined with single-cell RNAseq and in situ sequencing achieves high-throughput retrograde projection mapping and synaptic connectivity mapping at cellular resolution.

Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm² has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.

RiboD-PETRI, a cost-effective, equipment-free plate-based scRNA-seq technique that integrates a unique bacterial rRNA depletion protocol, significantly enhancing mRNA detection rate and revealing within-population heterogeneity, offering valuable insights for research applications.

An increase in transcriptional noise generally assumed to characterize aged cells and tissues is shown to derive instead from technical and biological issues that underlie single-cell RNA sequencing experiments.

A new disposition mechanism for glucuronides, where liver serves as recycle organ and intestine serves as metabolism organ, is established to better explain the disposition of phenolics in vivo.

The common view that the mitochondrion endowed eukaryotes with a boost in bioenergetic capacity above that in prokaryotes is inconsistent with a diversity of cellular features.

Structural analysis of the mitoribosomal small subunit with streptomycin reveals the molecular basis for antibiotic binding and new physiological components such as FeS clusters that assemble between mitochondria specific proteins.

Single-cell RNA-sequencing identifies the precise cellular and molecular events that occur along the sepsis timeline in the kidney, pointing to potential biomarkers and therapeutic targets.

aLENS implements new parallel methods to resolve cytoskeletal assembly dynamics with high stability, physical consistency, and scalability.