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    1. Computational and Systems Biology
    2. Physics of Living Systems

    Chemotactic smoothing of collective migration

    Tapomoy Bhattacharjee, Daniel B Amchin ... Sujit Sankar Datta
    Studies of bacterial chemotaxis reveal how limitations in single-cell sensing of stimuli influence large-scale population morphology.
    1. Cell Biology
    2. Neuroscience

    Specific labeling of synaptic schwann cells reveals unique cellular and molecular features

    Ryan Castro, Thomas Taetzsch ... Gregorio Valdez
    The discovery of markers specific to perisynaptic Schwann cells will accelerate the discovery of mechanisms important for their differentiation and function.
    1. Microbiology and Infectious Disease

    An improved bacterial single-cell RNA-seq reveals biofilm heterogeneity

    Xiaodan Yan, Hebin Liao ... Yingying Pu
    RiboD-PETRI, a cost-effective, equipment-free plate-based scRNA-seq technique that integrates a unique bacterial rRNA depletion protocol, significantly enhancing mRNA detection rate and revealing within-population heterogeneity, offering valuable insights for research applications.
    1. Microbiology and Infectious Disease
    2. Immunology and Inflammation

    Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli

    Sharon A McGrath-Morrow, Jarrett Venezia ... Alan L Scott
    A pre-clinical model of E. coli pneumonia reveals attenuated dynamics of MHCII-expressing mononuclear cells in neonatal lung associated with elevated susceptibility to bacterial pneumonia.
    1. Computational and Systems Biology

    Toward the cellular-scale simulation of motor-driven cytoskeletal assemblies

    Wen Yan, Saad Ansari ... Michael Shelley
    aLENS implements new parallel methods to resolve cytoskeletal assembly dynamics with high stability, physical consistency, and scalability.
    1. Cell Biology

    PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis

    Shuxian Li, Lingbing Li ... Xietong Wang
    Airborne PM2.5 exposure triggers oxidative stress and mitochondrial apoptosis in placental trophoblast cells via the KLF9/CYP1A1 transcriptional axis, ultimately leading to adverse pregnancy outcomes.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Respiro-Fermentation: To breathe or not to breathe?

    Lauren C Radlinski, Andreas J Bäumler
    Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.
    Version of Record
    Insight
    1. Cell Biology

    Magnetic resonance measurements of cellular and sub-cellular membrane structures in live and fixed neural tissue

    Nathan H Williamson, Rea Ravin ... Peter J Basser
    Low-field single-sided magnetic resonance diffusion methods detect and measure permeability of sub-micron compartments which likely include cell processes, organelles, and cellular vesicles within ex vivo mouse spinal cords.
    1. Biochemistry and Chemical Biology

    Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control

    Marta Carroni, Kamila B Franke ... Axel Mogk
    Head-to-head interactions of regulatory coiled-coil domains control activity of the central bacterial AAA+ protein ClpC by promoting formation of a reversible resting state.
    1. Cell Biology

    Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast

    Grant A King, Jay S Goodman ... Elçin Ünal
    A meiotic nuclear remodeling event mediates cellular rejuvenation through elimination of senescence factors.