A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.
A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.
Anca M Farcas, Neil P Blackledge ... Robert J Klose
A protein that can recognize regions of DNA with a high proportion of unmethylated CpG dinucleotides, and then recruit polycomb group proteins to these CpG islands, has been identified.
Alexandre Martinière, Aurélie Bak ... Martin Drucker
Cauliflower mosaic virus reacts immediately when aphids feed on the host plant, and this boosts its chances of being taken up and transmitted by the insects to a new plant.
The Notch signaling pathway has a central role in the development of the nervous system, and also in the establishment of networks of connections in the adult brain
Carmela Sidrauski, Diego Acosta-Alvear ... Peter Walter
A compound that prevents stressors such as UV light and viral infection from downregulating protein synthesis inside cells improves memory performance in mice.
In contrast to current models, inputs from midbrain limbic structures, but not from the hippocampus, are necessary for mammillary body contributions to memory.