A transcriptome dataset of nearly 200 genetically identified mouse neuronal cell types revealed that short low-noise homeobox transcription factors and long neuronal effector genes best distinguish neuronal cell types.
The coding sequences of a very highly conserved family of neurogenic transcription factors from different species have evolved to generate proteins that have different life times causing them to display quantitatively different neural induction potentials.
Attenuated anticipatory activity in ventromedial prefrontal cortex is modulated by dopamine D1 receptor density in nucleus accumbens, and accounts for impaired probabilistic reward learning in older adults.
The importance of synchronous Purkinje cell complex spikes for controlling cerebellar output was investigated by simultaneously recording from cerebellar nuclear cells and arrays of Purkinje cells that synapse onto them.
The electroconvulsive therapy induced electric field magnitude and laterality is related to volumetric increases in cortical and subcortical structures, but the association with clinical outcomes remains elusive.