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    1. Neuroscience

    AMPAR/TARP stoichiometry differentially modulates channel properties

    Federico Miguez-Cabello et al.
    A variable number of auxiliary subunit molecules (TARPs) accompanying AMPARs have a differential impact on channel behavior showing also striking differences between AMPAR subtypes.
    1. Neuroscience

    GluA4 facilitates cerebellar expansion coding and enables associative memory formation

    Katarzyna Kita et al.
    GluA4-containing AMPA receptors are required for effective excitation of cerebellar granule cells and enable expansion coding and associative learning.
    1. Developmental Biology
    2. Neuroscience

    Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

    Ryan T Willett et al.
    The first born excitatory cerebellar nuclei neurons influence the survival of their Purkinje cell partners which stimulate the expansion of granule cells and interneurons to produce functional local circuits.
    1. Developmental Biology
    2. Neuroscience

    Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons

    Eljo Van Battum et al.
    3D imaging and time-lapse video-microscopy show that the PlexinB2 receptor controls the tempo of granule cell differentiation and sets the pace of their migration in mouse cerebellum.
    1. Neuroscience

    Selective targeting of unipolar brush cell subtypes by cerebellar mossy fibers

    Timothy S Balmer, Laurence O Trussell
    Distinct inputs to the cerebellum make contact on specific subtypes of target neurons.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

    Markus Terrey et al.
    The translational GTPase GTPBP1 prevents ribosome stalling during tRNA deficiency and is necessary for neuronal survival.
    1. Developmental Biology
    2. Neuroscience

    Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms

    Parthiv Haldipur et al.
    Building on previous work (Haldipur et al., 2014), we show that many key mechanisms controlling cerebellar development are likely conserved between mouse and human, and validate our mouse model of Dandy-Walker malformation.
    1. Cell Biology
    2. Neuroscience

    High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect

    Daniel Medina-Cano et al.
    Impairment of protein N-glycosylation disrupts neural cell adhesion mediated by highly glycosylated members of the IgSF-CAM protein family.
    1. Neuroscience

    A novel inhibitory nucleo-cortical circuit controls cerebellar Golgi cell activity

    Lea Ankri et al.
    The glycinergic neurons of the cerebellar nuclei project extensively to the cerebellar cortex and inhibit GABAergic Golgi cells.
    1. Neuroscience

    Cannabinoids modulate associative cerebellar learning via alterations in behavioral state

    Catarina Albergaria et al.
    Cannabinoid receptors modulate cerebellar learning, not through direct effects on synaptic plasticity, but as a secondary consequence of their modulation of behavioral state.