586 results found
  1. June 2015

    Episode 21: June 2015

    In this episode we hear about tinnitus and hyperacusis, salamanders, chemical harpoons, and the role of ultrasound and song in the mating rituals of mice and flies.
    1. Physics of Living Systems

    Spatial control of neuronal metabolism through glucose-mediated mitochondrial transport regulation

    Anamika Agrawal et al.
    A quantitative analysis of glucose-dependent transport regulation indicates that mitochondrial accumulation in regions of high nutrient availability can enhance metabolism in neuronal axons under physiologically relevant conditions.
    1. Neuroscience

    Motor thalamus supports striatum-driven reinforcement

    Arnaud L Lalive et al.
    While the basal ganglia have long been thought to mediate learning through dopamine-dependent striatal plasticity, their regulation of motor thalamus plays an unexpected and critical role in reinforcement.
    1. Cancer Biology

    miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis

    Lihua Wang et al.
    miR-34a prevents inflammation-induced colonic regeneration from oncogenesis by simultaneously targeting processes in both immune and epithelial cells, including T helper 17 cell differentiation, recruitment, and IL-17 induced epithelial proliferation.
    1. Neuroscience

    Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion

    Adriane G Otopalik et al.
    Reliable neuronal physiology can arise from variable and inefficient morphologies.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Genetic mapping of etiologic brain cell types for obesity

    Pascal N Timshel et al.
    Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.
    1. Neuroscience

    Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms

    Kyungdeok Kim et al.
    Presynaptic adhesion molecule PTPσ in the hippocampus regulates postsynaptic NMDA receptor function and behavioral novelty recognition through mechanisms independent of their trans-synaptic binding partners.
    1. Computational and Systems Biology
    2. Neuroscience

    Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants

    Laura Cornelissen et al.
    Alpha EEG oscillations emerge at 4 months of age during sevoflurane general anesthesia, and unlike in adults, have a widespread spatial distribution that likely reflects differences in brain development.
    1. Neuroscience

    Extrinsic and intrinsic dynamics in movement intermittency

    Damar Susilaradeya et al.
    The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.
    1. Neuroscience

    Neuronal morphologies built for reliable physiology in a rhythmic motor circuit

    Adriane G Otopalik et al.
    Neurite geometry enables expansive and highly-branched neuronal structures to operate like single electrical compartments and simple linear integrators.

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