5,270 results found
    1. Neuroscience

    Likelihood approximation networks (LANs) for fast inference of simulation models in cognitive neuroscience

    Alexander Fengler, Lakshmi N Govindarajan ... Michael J Frank
    A novel method and software provides researchers with the capability to rapidly, flexibly, and robustly perform Bayesian parameter estimation of theoretically meaningful models in cognitive neuroscience that were heretofore intractable.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

    Amy R Strom, Ronald J Biggs ... Andrew D Stephens
    Micromanipulation experiments demonstrate that HP1α strengthens interphase and mitotic chromosome mechanics and maintains nuclear shape by chromatin crosslinking, separate from histone methylation.
    1. Computational and Systems Biology
    2. Neuroscience

    Flexible theta sequence compression mediated via phase precessing interneurons

    Angus Chadwick, Mark CW van Rossum, Matthew F Nolan
    A new model for phase precession accounts for theta sequence generation, suggests critical roles for interneurons, and predicts circuit properties to optimise memory storage.
    1. Neuroscience

    Lapses in perceptual decisions reflect exploration

    Sashank Pisupati, Lital Chartarifsky-Lynn ... Anne K Churchland
    During perceptual decision-making, some errors on easy decisions (lapses) are not simply mistakes, but instead reflect strategic decisions to explore actions associated with uncertain rewards.
    1. Neuroscience

    Statistical inference on representational geometries

    Heiko H Schütt, Alexander D Kipnis ... Nikolaus Kriegeskorte
    New methods for statistical inference in representational similarity analysis were developed, tested thoroughly, and are made available in an open-source Python toolbox.
    1. Physics of Living Systems

    Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law

    Thomas C Day, Stephanie S Höhn ... Peter J Yunker
    The distributions of cellular neighborhood volumes in two very different multicellular species - snowflake yeast and Volvox carteri - are found to obey a common functional form arising from maximum entropy consideration, despite great differences in their cell division processes.
    1. Plant Biology

    Arabidopsis plants perform arithmetic division to prevent starvation at night

    Antonio Scialdone, Sam T Mugford ... Martin Howard
    Plants implement arithmetic division to optimize use of carbohydrate reserves and thus maintain metabolism and growth at night.
    1. Genetics and Genomics

    Minimal-assumption inference from population-genomic data

    Daniel B Weissman, Oskar Hallatschek
    The coalescent history of a population can be learned just from the present genomic diversity, without having detailed prior knowledge of the pattern of recombination or the forces driving coalescence.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Pyphe, a python toolbox for assessing microbial growth and cell viability in high-throughput colony screens

    Stephan Kamrad, María Rodríguez-López ... Jürg Bähler
    An open-source python package for phenotype analyses provides a versatile, modular and user-friendly solution to determine complementary fitness-related traits from large-scale assays of microbial colonies.
    1. Neuroscience

    LabNet hardware control software for the Raspberry Pi

    Alexej Schatz, York Winter
    A software distributed platform for the Raspberry Pi to simplify and unify hardware access over the Ethernet network with almost real-time latencies.

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