Barcoded rabies virus tracing combined with single-cell RNAseq and in situ sequencing achieves high-throughput retrograde projection mapping and synaptic connectivity mapping at cellular resolution.
Electron-microscopy reconstruction and experimental investigation in Drosophila reveal how adaptive action emerges from the multi-level interactions between the output of the olfactory memory center and the innate olfactory pathway.
The isolation of the cell membrane of single cells coupled with AFM enables the study and identification of native membrane proteins in a membrane fragment.
Víctor J López-Madrona, Elena Pérez-Montoyo ... Santiago Canals
Integration and segregation of information of memory and sensory in the hippocampus could be achieved by the coordination of distinct theta-gamma coding frameworks.
A fully automated workflow for high-throughput mouse behavioral and optogenetic experiments in homecage reveals involvement of brain regions in tactile decision-making.
Soo Ji Baek, Jin Sung Park ... Keiko Tanaka-Yamamoto
Long-term chemogenetic manipulation of specific cerebellar pathway involving ventral tegmental area revealed a critical role of the pathway as a proactive mediator of the stress-dependent development of depression-like behaviors.