An electroporation-based method allows the direct delivery of recombinant proteins into mammalian cells for in vivo functional studies.

Upon detecting a fatal infection using chemical cues, ants puncture the cuticle of sick brood and inject antimicrobial poison that disrupts the pathogen's life cycle and prevents it from reproducing, thus protecting the colony from disease.

Chemical nestmate recognition in honey bee colonies depends on an innate, socially modulated developmental process.

A chemical biology approach has identified the kinase DYRK1A as a new regulator of the inflammatory response.

The socially exchanged fluid passed mouth-to-mouth during trophallaxis contains molecules that can influence development, potentially mediating communal control of colony phenotypes.

The widespread occurrence of metabolically active streptomycetes in Odontotaenius disjunctus beetle frass may insulate their galleries against pathogenic fungal invasion through the production of diverse antimicrobial specialized metabolites.

A network of the gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs and supports the generation of mechanistic hypotheses of microbiome metabolic phenotypes that shape human biology.

Sphingosine acts as a lipid messenger molecule in intracellular signaling networks that are relevant to lysosomal function and Niemann-Pick disease.

A combination of mathematical modeling and live-cell imaging reveals a strategy for the rational control over cell electrophysiology though modulation of ion channel expression.

Protein phase separation provides an explanation for the compositional flexibility of endocytic initiation and the role of multivalent disordered scaffolds in endocytosis.