4,028 results found
    1. Neuroscience

    Parallel processing of quickly and slowly mobilized reserve vesicles in hippocampal synapses

    Juan Jose Rodriguez Gotor, Kashif Mahfooz ... John F Wesseling
    Reevaluation of reserve synaptic vesicle pools supports a new model of presynaptic function.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Dynamic metastable long-living droplets formed by sticker-spacer proteins

    Srivastav Ranganathan, Eugene I Shakhnovich
    Multi-scale simulations reveal a potential, ATP-independent mechanism resulting in the formation of the long-living multi-droplet state by multi-valent, spacer-sticker proteins.
    1. Ecology

    The larva and adult of Helicoverpa armigera use differential gustatory receptors to sense sucrose

    Shuai-Shuai Zhang, Pei-Chao Wang ... Chen-Zhu Wang
    The sweet taste receptors in the cotton bollworm (Helicoverpa armigera) are evolved to adapt towards the larval and adult foods with different types and amounts of sugar.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The autophagic membrane tether ATG2A transfers lipids between membranes

    Shintaro Maeda, Chinatsu Otomo, Takanori Otomo
    The autophagy protein ATG2A tethers membranes and transfers lipids between them, suggesting that autophagosome membranes grow upon the acquisition of lipids from the ER through the ATG2A bridge.
    1. Neuroscience

    Drosulfakinin signaling modulates female sexual receptivity in Drosophila

    Tao Wang, Biyang Jing ... Chuan Zhou
    The neuropeptide Drosulfakinin (DSK) functions in a subset of DSK neurons to interact with neural nodes in the sex circuit and acts through its receptor CCKLR-17D3 to control female sexual behavior.
    1. Structural Biology and Molecular Biophysics

    A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

    Danish Khan, Dongju Lee ... Vytas A Bankaitis
    A new class of fungal hemoproteins is described that emphasizes the versatility of the Sec14-fold for translating binding of chemically distinct ligands to control of diverse sets of cellular activities.
    1. Cell Biology
    2. Neuroscience

    The synaptic ribbon is critical for sound encoding at high rates and with temporal precision

    Philippe Jean, David Lopez de la Morena ... Tobias Moser
    The synaptic ribbon regulates calcium channel clustering and proper vesicle dynamics at cochlear inner hair cells to ensure precise sound encoding.
    1. Genetics and Genomics
    2. Plant Biology

    Natural epigenetic polymorphisms lead to intraspecific variation in Arabidopsis gene imprinting

    Daniela Pignatta, Robert M Erdmann ... Mary Gehring
    Individual scientists, scientific communities and scientific journals can do more to assess the publication of irreproducible results, to promote good science, and to increase the efficiency with which the scientific community self-corrects.
    1. Ecology

    The push–pull intercrop Desmodium does not repel, but intercepts and kills pests

    Anna L Erdei, Aneth B David ... Teun Dekker
    Instead of repelling, Desmodium, a hallmark of pest suppressive sustainable intercropping, acts as a mechanical and developmental barrier to larvae, thereby truncating population development.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq

    Jason G Dumelie, Samie R Jaffrey
    Genome-wide profiling of R-loops at near single-nucleotide resolution reveals distinct R-loop boundaries depending on the presence and location of the first exon-intron junction.

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