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    1. Plant Biology

    Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors

    Alexey Shapiguzov, Julia P Vainonen ... Jaakko Kangasjärvi
    Signalling and metabolic interactions of the plant energy organelles, chloroplasts and mitochondria, depend on the nuclear regulatory protein RCD1.
    1. Ecology
    2. Genetics and Genomics

    Decoding the genetic and chemical basis of sexual attractiveness in parasitic wasps

    Weizhao Sun, Michelle Ina Lange ... Jan Buellesbach
    How biologically relevant chemical information can be genetically maintained and conveyed in complex sex pheromonal profiles.
    1. Computational and Systems Biology

    Modular, robust, and extendible multicellular circuit design in yeast

    Alberto Carignano, Dai Hua Chen ... Eric Klavins
    Multicellular systems exhibiting a wide variety of behaviors, including logic gates, band-pass filtering, and bistability, are constructed from a fixed vocabulary of input-output strains through model-guided design demonstrating predictable composability, tunability, and extendability.
    1. Neuroscience

    Circuit mechanisms encoding odors and driving aging-associated behavioral declines in Caenorhabditis elegans

    Sarah G Leinwand, Claire J Yang ... Sreekanth H Chalasani
    Neurotransmission pathways from primary to secondary neurons encode odor and underlie age-related sensory behavioral declines.
    1. Neuroscience

    Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence

    Eun Jo Du, Tae Jung Ahn ... KyeongJin Kang
    Electron-donating nucleophilic compounds activate TRPA1 ion channels in fruit flies and mosquitoes, but not humans, making TRPA1 a promising target for insect repellants.
    1. Microbiology and Infectious Disease

    A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane

    Anna Konovalova, Angela M Mitchell, Thomas J Silhavy
    Mutations that block assembly of the interlocked RcsF/β barrel protein complex prevent detection of lipopolysaccharide stress and activation of Rcs signal transduction pathway.
    1. Ecology

    Dynamic metabolic exchange governs a marine algal-bacterial interaction

    Einat Segev, Thomas P Wyche ... Roberto Kolter
    Physical and chemical interactions with bacteria influence the life and death of Emiliania huxleyi, a bloom-forming micro-alga important in global biogeochemical cycles.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Molecular basis for the adaptive evolution of environment-sensing by H-NS proteins

    Xiaochuan Zhao, Umar F Shahul Hameed ... Jianing Li
    Combining in silico and experimental approaches to identify and understand the residue changes in the H-NS protein that allowed bacteria to adapt environment-sensing to different habitats.
    1. Plant Biology

    A hypothesis on the capacity of plant odorant-binding proteins to bind volatile isoprenoids based on in silico evidences

    Deborah Giordano, Angelo Facchiano ... Francesco Loreto
    It is hypothesized that volatile organic compounds emitted by plants after stress induction may be sensed by neighboring eavesdropping plants using odorant-binding proteins.
    1. Structural Biology and Molecular Biophysics

    Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

    Amanda F Clouser, Hannah ER Baughman ... Rachel E Klevit
    Multiple iso-energetic-specific interactions involving the intrinsically-disordered region of sHSP HSPB1 define a quasi-ordered state, providing insights into inherited disease-associated mutations within the region that are thought to be disordered.