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Structural Biology and Molecular Biophysics
Activation of the archaeal ion channel MthK is exquisitely regulated by temperature
Yihao Jiang et al.
Temperature-sensitivity of archaebacterial potassium channel MthK is regulated by RCK domain via alteration of allosteric coupling.
Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe
Virginia E Hawkins et al.
-dependent purinergic signaling by astrocytes provides specialized control of vascular tone in a brainstem respiratory center in a manner that contributes to respiratory behavior.
COPI selectively drives maturation of the early Golgi
Effrosyni Papanikou et al.
Inactivation of the COPI vesicle coat in yeast reveals that COPI recycles early but not late Golgi proteins.
Somatostatin-expressing parafacial neurons are CO
sensitive and regulate baseline breathing
Colin M Cleary et al.
Cellular and chemogenetic approaches identify a novel mode of chemotransduction involving regulation of basal breathing by CO
TRPV4 is the temperature-sensitive ion channel of human sperm
Nadine Mundt et al.
The molecular identity of the temperature-sensitive ion channel of human sperm that ensures depolarization is TRPV4.
Chemoreception: Keeping carbon dioxide in check
Alfredo J Garcia III, Jan-Marino Ramirez
The response of the brainstem to increased levels of carbon dioxide in the blood is coordinated with the response of the cardiovascular system.
Chromosomes and Gene Expression
Genetics and Genomics
The deubiquitylase Ubp15 couples transcription to mRNA export
Fanny Eyboulet et al.
Ubp15 regulates the ubiquitylation of the export adaptor Mex67.
Feeding state functionally reconfigures a sensory circuit to drive thermosensory behavioral plasticity
Asuka Takeishi et al.
Starvation modulates thermotaxis behaviors in
via functional reconfiguration of a sensory network by gut-brain signaling.
Vascular control of the CO
-dependent drive to breathe
Colin M Cleary et al.
Understanding how loss of CO
vascular reactivity affects respiratory control may facilitate development of treatments for breathing problems in this population.
Astrocytic modulation of excitatory synaptic signaling in a mouse model of Rett syndrome
Benjamin Rakela et al.
Astrocytes impact neuronal signaling in brain dependent on status of the transcriptional repressor, Methyl CpG Binding Protein 2.
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